Illustration of the structure of a targeted protein degrader molecule, such as a proteolysis-targeting chimera (PROTAC). Targeted protein degraders are small molecules consisting of two ligands (yellow and cyan) joined by a linker (purple). One ligand recruits a protein of interest, while the other recruits a protein ligase molecule, which leads to the ubiquitylation and subsequent degradation of the protein of interest. | |
Licence : | Libre de droits |
Crédit: | Science Photo Library / THOM LEACH |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |