Illustration of a human telomeric DNA (deoxyribonucleic acid) G-quadruplex bound to a naphthalene diimide. Telomere DNA G-quadruplexes are four-stranded DNA structures that are found in the telomere regions at the ends of chromosomes. Telomeres are regions of repeated non-coding nucleotides that prevent coding nucleotides being lost during DNA replication. Telomeres shorten over time and this process is thought to play a role in cancer and ageing. Binding of naphthalene diimides can stabilise the telomeres and so they are being investigated for their anticancer activity. | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / FRANCISCO J. ENGUITA |
Taille de l’image : | 4859 px × 4832 px |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |