Craniopharyngioma, light micrograph

Numéro d’image : 13296450
Craniopharyngioma, light micrograph
Craniopharyngioma, light micrograph. Craniopharyngioma is a WHO Grade 1 epithelial tumour usually seen in the sellar/suprasellar region. It arises most likely from the remnants of Rathke's pouch. Some cases may have their origin in misplaced odontogenic rests along pituitary stalk. Grossly, they are often solid and cystic with areas of calcification. Craniopharyngiomas are subdivided into two types based on morphologic features: 1) Adamantinomatous (90% of cases) seen mostly in children and 2) Papillary (10% of cases) seen mostly in adults. This image shows most of the key diagnostic features of an adamantinomatous craniopharyngioma: a) sheets of squamous epithelial cells with peripheral palisading (best seen along the bottom of the image); b) a loose meshwork of epithelial cells called the stellate reticulum; c) nodules of anucleated squames (ghost cells) with brightly eosinophilic cytoplasm termed wet keratin. Wet keratin is considered diagnostic even in the absence of viable epithelium.
Licence : Droits gérés
Crédit: Science Photo Library / WEBPATHOLOGY
Taille de l’image : 4096 px × 3200 px
Model Release : Non requis
Property Release : Non requis
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