Drug resistance in candidiasis infection, illustration

Numéro d’image : 13219828
Drug resistance in candidiasis infection, illustration
Drug resistance in candidiasis infection. Illustration of the cellular mechanism (inset at top) for drug resistance in an infection caused by the pathogenic yeast Candida auris (brown strands). C. auris causes serious multidrug-resistant infections in hospitalized patients and has high mortality rates. The infections are resistant to azole antifungal drugs, but are treatable with echinocandin antifungal drugs. The inset shows the azole antifungal drug fluconazole (yellow) and the key metabolic enzyme lanosterol 14 alpha-demethylase (blue) on a fungus cell membrane. Due to genetic mutations in the enzyme's active site (red), fluconazole can't bind to the enzyme and this fungus is resistant to this drug.
Licence : Droits gérés
Crédit: Science Photo Library / Gaertner, Juan
Taille de l’image : 6827 px × 5120 px
Model Release : Non requis
Property Release : Non requis
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