Small lymphocytic lymphoma, light micrograph

Numéro d’image : 12971497
Small lymphocytic lymphoma, light micrograph
Small lymphocytic lymphoma, light micrograph. B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma are the most common mature B-cell neoplasms and are considered to be different manifestations of the same disease. Chronic lymphocytic leukemia affects middle-aged and elderly patients. The mature-appearing neoplastic B-cells are predominantly in blood and bone marrow. In small lymphocytic lymphoma, the neoplastic cells are mainly extramedullary with very few leukemic cells in blood. In 5% to 10% of patients with chronic lymphocytic leukemia / small lymphocytic lymphoma, the disease undergoes transformation to a more aggressive tumor, usually in the form of a diffuse large B-cell lymphoma, as shown in this image. This phenomenon is known as Richter Syndrome. The prognosis is extremely poor.
Licence : Droits gérés
Crédit: Science Photo Library / WEBPATHOLOGY
Taille de l’image : 4730 px × 3695 px
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