Benign prostatic hyperplasia (BPH), light micrograph. BPH, also called prostate enlargement, is a noncancerous increase in size of the prostate. It is an extremely common abnormality, with a frequency that rises progressively with age. BPH is characterized by proliferation of both stromal and epithelial elements, with resultant enlargement of the gland. BPH frequently appears as a nodular hyperplasia. Microscopically the hyperplastic nodules are composed of variable proportions of proliferating glandular elements. The nodules may contain cystic spaces, which are dilated glandular elements. There are also three nodules of stromal hyperplasia and some inflammatory infiltrates. | |
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