An illustration of Tay-sachs disease, a rare, inherited disorder that progressively destroys neurons in the brain. Tay-sachs is most commonly seen during infancy as development begins to slow and muscles begin to weaken. Fatty substances in the brain, known as GM2 gangliosides (green), are used as an energy source but become toxic in large concentrations. Children affected by Tay-sachs lack a lysosomal enzyme necessary to break down these fat molecules, due to a mutated gene. The disease eventually progresses into seizures, vision and hearing loss, intellectual disability, and paralysis as more neurons absorb these toxic fats without the ability to break them down. As a result, most infants only live until early childhood. | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Oto, Evan |
Taille de l’image : | 3300 px × 2550 px |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |