Signet ring cell carcinoma of the colon, light micrograph

Numéro d’image : 12504397
Signet ring cell carcinoma of the colon, light micrograph
Signet ring cell carcinoma of the colon, light micrograph. This is a rare form of adenocarcinoma, a cancer of the glandular lining that is found in many different organs, including the digestive tract. Colon cancer is one of the most common cancers in North America and Western Europe. It is thought to be connected to a diet high in fat and low in fibre. Signet ring cell carcinoma makes up around 1 percent of all colorectal cancers. The signet ring cells are arranged in diffuse sheets, small nests, or clusters. The oval or crescent nuclei are hyperchromatic and pushed to the periphery by intracellular mucin. Here, the tumour is infiltrating through muscularis propria, and the tumour cells are surrounded by extracellular mucin. The tumour spreads via peritoneal dissemination and has an extremely poor prognosis.
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Crédit: Science Photo Library / WEBPATHOLOGY
Taille de l’image : 4730 px × 3695 px
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