Stages of autophagy, illustration

Numéro d’image : 12375435
Stages of autophagy, illustration
Stages of autophagy, illustration. Autophagy (autophagocytosis) is the natural mechanism that destroys unnecessary or dysfunctional cellular components. The cell nucleus is at left (round), surrounded by folds of the endoplasmic reticulum. The five stages of autophagy shown here (anti-clockwise from bottom left) are: formation of isolation membrane; collection of cellular components for degradation; completion of formation of autophagosome, fusion of autophagosome with lysosome; and formation of autolysosome and degradation of contents. Lysosomes contain hydrolytic enzymes that break down many biological molecules. The 2016 Nobel Prize in Physiology or Medicine was awarded to Japanese cell biologist Yoshinori Ohsumi for his discoveries of mechanisms for autophagy. For this artwork without labels and without labels and arrows, see images C030/3439 and C030/3440.
Licence : Droits gérés
Crédit: Science Photo Library / Elam, Gunilla
Taille de l’image : 3300 px × 4400 px
Model Release : Non requis
Property Release : Non requis
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