Caspase-1 molecule. Computer model showing caspase-1 complexed with small inhibitors (red). Caspase-1 is a protease, an enzyme that cleaves proteins. It is found predominantly in the cell cytoplasm, where it activates interleukin-1-beta, a molecule that mediates immune and inflammatory responses. Due to this activity caspase-1 is also known as ICE (interleukin-1-beta converting enzyme). Like other caspases it also plays a role in apoptosis (programmed cell death), but only when over-expressed. | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Laguna Design |
Taille de l’image : | 4180 px × 4180 px |
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Property Release : | Non requis |
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