Extracellular matrix, SEM

Numéro d’image : 12298229
Extracellular matrix, SEM
Extracellular matrix (ECM) produced by dermal fibroblasts, coloured scanning electron micrograph (SEM).The ECM is a complex structural tissue component surrounding and supporting cells in mammalian tissues. It is composed of 3 major classes of biomolecules: 1) Structural proteins - collagen and elastin, 2) Specialized proteins - such as: fibrillin, fibronectin, and laminin and 3) Proteoglycans - complex proteins and long chains of repeating disaccharide units called glycosaminoglycans (GAGs, such as: hyaluronic acid, chondroitin sulphate, heparin, heparan sulphate). Collagens are the most abundant proteins found in the animal kingdom. It is the major protein comprising the ECM. Many cells bind to components of the extracellular matrix. The cell to ECM adhesion is regulated by specific cell surface cellular adhesion molecules (CAM) known as integrins. The integrins transmit mechanical stimuli from the ECM to the cytoskeleton. Magnification: x1, 000
Licence : Droits gérés
Crédit: Science Photo Library / DENNIS KUNKEL MICROSCOPY
Taille de l’image : 2726 px × 3206 px
Model Release : Non requis
Property Release : Non requis
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