Januvia (sitagliptin) is a hypoglycemic drug,one that reduces blood sugar levels. Diabetes is a condition in which blood sugar levels can get dangerously high due to a lack of insulin,the hormone that reduces them. Januvia works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). DPP-4 rapidly deactivates the incretin hormone GLP-1 (glucagon-like peptide 1),which promotes insulin release. Hence,inhibiting DPP-4 prolongs the effects of GLP-1,keeping insulin levels high | |
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