Artwork entitled "Inside the AIDS Virus",showing a possible mechanism by which the Human Immunodeficiency Virus (HIV) disables the immune system through the interaction of a monocyte (blue) & a T4 cell (pink). In a normal immune response,monocytes function to engulf & process foreign antigens,presenting fragments (as MHC molecules) for recognition by receptors (CD4) on T4 cells. However,HIV also binds to CD4 & may prevent this antigen presentation. Here,an antigen presented by the monocyte appears yellow. The cup-shaped CD4 is filled with HIV protein (green) & so is "blind" to the MHC and the antigen. Thus the immune response is cancelled. First published New Scientist,10 February 1990 | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Gifford, David |
Taille de l’image : | 5527 px × 4458 px |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |