Sirtuin enzyme and p53. Computer artwork of a sirtuin (Sir2) enzyme (pink) bound to a p53 peptide (orange). Sir2 enzymes form a unique class of NAD(+)-dependent deacetylases that are required for diverse biological processes,including transcriptional silencing,regulation of apoptosis (programmed cell death),fat mobilisation,and lifespan regulation. NAD is shown as a stick model (centre). p53 is crucial in multicellular organisms,where it regulates the cell cycle (the means by which cells replicate) and prevents the proliferation of cells with damaged DNA | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Andrade, Ramon / 3dciencia |
Taille de l’image : | 3623 px × 4830 px |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |