Growth hormone receptor. Molecular model of a growth hormone receptor (orange) in a plasma membrane. Binding of growth hormone to the receptor rotates the receptor molecule subunits,changing the alignment of the intracellular (bottom) part of the protein. This activates the tyrosine kinase JAK2 (pink,bottom right),which initiates a number of changes within the cell that activate specific genes. Growth hormone stimulates growth,especially in childhood,strengthens bone,increases muscle mass,reduces glucose uptake by the liver and promotes the breakdown of body fat | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Andrade, Ramon / 3dciencia |
Taille de l’image : | 3524 px × 4983 px |
Model Release : | Non requis |
Property Release : | Non requis |
Restrictions : | - |