DNA missense point mutation. Animation showing a missense point mutation in the replication of DNA (deoxyribonucleic acid). As the DNA unravels, a helicase enzyme (red) is shown moving along the helix, separating the complementary strands. Labels appear showing the genetic code, the sequence of the nucleotide bases along a strand (cytosine, C, blue; guanine, G, yellow; adenine, A, green; thymine, T, red). A DNA polymerase enzyme is shown replicating a new strand and making a mistake (red area). The new complementary strands are formed, completing the replication process and the animation zooms in on the mistake (a mutation). Adjacent groups of three bases, known as codons, code for the production of amino acids (the basis of proteins). The codon affected here is GTA (for the amino acid valine). This has mutated to GAA, which will produce a different amino acid (glutamic acid). This is known as a missense mutation, as opposed to mutations that produce nonsense or no change (a silent mutation). | |
Licence : | Droits gérés |
Crédit : | Science Photo Library / EQUINOX GRAPHICS / RHYS LEWIS, AHS, DECD, UNISA |
Model Release : | Non requis |
Durée : | 40 Secondes |
Aspect ratio : | 16/9 |
Restrictions : | - |