B-cell maturation and clonal selection

Référence de la vidéo 11938292
B-cell maturation and clonal selection. Animation showing the process by which a type of white blood cell, the B-lymphocytes, mature in the lymph nodes (one at left). The opening stages of the animation show three immature B cells (blue, red nucleus) with antibodies (orange) on their surfaces. They are exposed to the same antigen (red dot). At left and right, this antigen does not fit with the antibodies, so no reaction takes place. The antigen is recognised by the antibodies of the middle B cell, which then proceeds to mature through a series of clonal steps shown here. The end results (at end of animation) are plasmocytes (or plasma B cells). These are mature B cells able to produce specific antibodies against this antigen. The other products of the maturation process are memory cells. These are kept in reserve to be activated during a second or later contact with the same antigen. This maturation of B cells takes place in germination centres in the lymph nodes. For this animation without labels, see K004/4170.
Licence : Droits gérés
Crédit : Science Photo Library / Biocosmos / Francis Leroy & Marie Martinache
Model Release : Non requis
Durée : 27 Secondes
Aspect ratio : 16/9
Restrictions : -

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