Adenylate cyclase regulation mechanism

Référence de la vidéo 11937917
Adenylate cyclase regulation mechanism. Animation showing the activation and inhibition of the enzyme adenylate cyclase (blue, centre), also known as adenylyl cyclase. The activity of this cell membrane enzyme depends on stimulation and inhibition signals by G-proteins (guanosine nucleotide-binding proteins). Gs proteins are stimulatory, while Gi ones are inhibitory, both prompted here by hormone receptors (green, far left; red, far right). The G-proteins here are heterotrimeric, consisting of alpha, beta and gamma subunits. In each case, a molecule of GTP (guanosine triphosphate, yellow dots) replaces the GDP (guanosine diphosphate) bound to the G-protein complex. Depending on whether the G-protein belongs to the stimulatory or inhibitory pathway, the effect is to control the conversion of ATP (adenosine triphosphate) to 3', 5'-cyclic adenosine monophosphate (cAMP). For this animation without labels, see K004/3650.
Licence : Droits gérés
Crédit : Science Photo Library / Biocosmos / Francis Leroy & Michael Pierard
Model Release : Non requis
Durée : 25 Secondes
Aspect ratio : 16/9
Restrictions : -

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