Citric acid cycle. Animation showing the eight steps in the citric acid cycle, the process by which mitochondria convert glucose to energy. At the start of the reaction acetyl CoA reacts with oxaloacetate (1) to form citrate (2), resulting in the release of coenzyme A (CoA-SH). Two water molecules are then lost to form isocitrate (4), which undergoes oxidation and the loss of a molecule of carbon dioxide (CO2) to form alpha-ketoglutarate (5). A second oxidation and the loss of a second molecule of CO2 forms succinyl CoA (6), which is converted to succinate (7) by the enzyme succinyl CoA synthetase. Oxidation of succinate produces fumarate (8), which is hydrated to form malate (9), which is oxidated to form oxaloacetate, enabling the cycle to begin again. | |
Licence : | Droits gérés |
Crédit : | Science Photo Library / Biocosmos / Francis Leroy & Edwin Vandermeeren |
Model Release : | Non requis |
Durée : | 60 Secondes |
Aspect ratio : | 16/9 |
Restrictions : | - |