Genetic basis of virus-induced cancers

Référence de la vidéo 11937688
Genetic basis of virus-induced cancers. Animation showing the genetic mechanism by which some viruses can induce cancer. The initial part of the animation shows cell proliferation factor (red, flashing) bound to a regulatory gene segment of DNA (deoxyribonucleic acid, blue and red). This is inactivated by a protein (yellow) expressed by the suppressor tumour gene Rb. Some viruses (such as the Papilloma viruses) disrupt this mechanism by producing proteins that bind to (sequester) the inactivating proteins. Here, the E7 protein (grey) binds to the Rb protein, leaving the cell proliferation factor to induce cell division which can result in cancer if not controlled. Another viral protein, E6 (green), acts on the protein (light blue) produced by the p53 suppressor tumour gene, with a similar effect. For this animation without labels, see K004/3400.
Licence : Droits gérés
Crédit : Science Photo Library / Biocosmos / Francis Leroy & Mathilde Vanspeybrouck
Model Release : Non requis
Durée : 44 Secondes
Aspect ratio : 16/9
Restrictions : -

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