Phosphinositide cascade, animation

Référence de la vidéo 11937576
Phosphinositide cascade, animation. The binding of a hormone (green sphere) to a receptor (pink) in the plasma membrane of a cell activates a G protein (orange). The G protein in turn activates phosphlipase C (yellow) a transmembrane enzyme that hydrolyses PIP2 (red) to inositol trisphosphate (IP3) and diacylglycerol (DAG, purple). Both of these substances act as second messengers, activating protein kinase C (brown). IP3 does this by stimulating the release of calcium ions (red spheres) from the endoplasmic reticulum (bottom). This increase in calcium ions activates protein kinase C. DAG activates it directly. Once activated protein kinase C can phosphorylate a number of proteins (red) to bring about a number of effects depending upon the cell.
Licence : Droits gérés
Crédit : Science Photo Library / Biocosmos / Francis Leroy & Nathan Petit
Model Release : Non requis
Durée : 01:09 Minutes
Aspect ratio : 16/9
Restrictions : -

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