Blood-brain barrier

Référence de la vidéo 11936437
Blood-brain barrier. Animation showing the cellular mechanisms that separate the blood vessels in the brain from the extracellular fluid. This blood-brain barrier, or haematoencephalic barrier, acts to protect the brain from bacterial infections. The barrier is formed by the brain capillary endothelium, with a small capillary vein shown in cross-section at top and from the side at lower left. Support cells called astrocytes play a crucial role, with their 'feet' covering the outer endothelial surface. The junctions between the endothelial cells are known as tight junctions. These junctions only allow small hydrophilic molecules to diffuse through, along with other substances that have specific transport mechanisms. At lower right, molecules shown passing the barrier include water (H2O, red and blue), some gases (red), amino acids (purple), glucose (green) and lipids (yellow). Large molecules and ions (red and green, plus and minus symbols) cannot pass the barrier. For this animation with labels, see K004/0954.
Licence : Droits gérés
Crédit : Science Photo Library / Biocosmos / Francis Leroy & Chris Lippens
Model Release : Non requis
Durée : 38 Secondes
Aspect ratio : 16/9
Restrictions : -

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