Golgi body oligosaccharide biochemistry. Animation showing possible reaction pathways for the transformation of oligosaccharides (sugar polymers) in cell structures known as Golgi bodies (also Golgi apparatus). This structure processes and packages proteins and other cellular substances. Shown at left are the flattened Golgi membrane discs known as cisternae, between the cis-Golgi network (upper left) and the trans-Golgi network (lower left). This clip shows steps in the transformation of an N-linked oligosaccharide and the amino acid (Asn, asparagine) to which it is attached. The cisterna involved is shown glowing at each step. The first step is the elimination of glucose residues (green) and a mannose residue (blue). This is followed by excision of other mannose sugars as well as addition of N-acetylglucosamine (GlcNAc) or sialic acids. These later steps involve the use of carrier chemicals such as UDP (uridine diphosphate) and CMP (cytidine monophosphate). The exact nature of this reaction has not yet been fully established and may differ from what is shown here. For this animation with labels, see K004/0937. | |
Licence : | Droits gérés |
Crédit : | Science Photo Library / Biocosmos / Francis Leroy & Guillaume Wilmotte |
Model Release : | Non requis |
Durée : | 56 Secondes |
Aspect ratio : | 16/9 |
Restrictions : | - |