Yersinia pestis infection mechanism, animation. Y. pestis (bottom) is the bacterium responsible for the bubonic plague. This is the type III secretion mechanism, which allows Y. pestis to inject toxins into a macrophage cell (top). Macrophages are immune system cells that phagocytose (engulf) and destroy pathogens. A Yersinia outer protein (YOP, red) perforates the macrophage cell membrane, creating a pore that allows toxins (green) to diffuse from the bacterium into the macrophage. The injected toxins interfere with macrophage function, compromising the immune system and allowing Y. pestis to proliferate. For an unlabelled version of this animation, see K004/0929. | |
Licence : | Droits gérés |
Crédit : | Science Photo Library / Biocosmos / Francis Leroy & Nathan Petit |
Model Release : | Non requis |
Durée : | 25 Secondes |
Aspect ratio : | 16/9 |
Restrictions : | - |