Allergic Cascade, Illustrated Flow Chart

Numéro d’image : 12651554
Allergic Cascade, Illustrated Flow Chart
Flow chart displaying illustrated steps of the allergic cascade and how an allergic response affects the eye. If the body comes in contact with an allergen, there are often two types of reactions that take place, an early-phase reaction and a late-phase reaction. During the early-phase reaction, an allergen (near top, red) binds with the antibody Immunoglobulin E (IgE, blue and yellow), which is connected to a mast cell (large circular structure, blue-green) white blood cell. Once the allergen binds to IgE, the mast cell releases histamine. These particles of histamine connect with H1 and H2 receptors on nerve tissue within the eye, therefore cause the eyes to become itchy, red and watery. During the late-phase reaction, the mast cell releases cytokines and prostaglandins in response to the allergen. The cytokine and prostaglandin particles then recruit inflammatory cells, which leads to fluid leakage and swelling within the eye.
Licence : Droits gérés
Crédit: Science Photo Library / Science Source
Taille de l’image : 2400 px × 4361 px
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