Light micrograph of a cervical smear revealing severe dysplasia (CIN 3),the presence of abnormal,blue-staining cells with large,dark nuclei. The CIN grading refers to a spectrum of potentially cancerous changes (dysplasia) in the stratified squamous epithelium that lines the cervix. CIN 1 corresponds to mild dysplasia,CIN 2 to moderate dysplasia & CIN 3 to severe dysplasia & carcinoma-in-situ. In a normal squamous epithelium,cell division is confined to the basal layer; cells mature & rise towards the surface. Normal superficial cells are pink staining,with small nuclei. Dysplastic cells represent a disruption in the maturation process | |
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Crédit: | Science Photo Library |
Taille de l’image : | 5046 px × 3492 px |
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