Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) bound to a DNA double strand break,molecular model. Human PARP-1 (Poly(ADP-ribose)-Polymerase-1) is a highly conserved protein (113 kDa) that is strongly activated by DNA strand breaks,and participates in modulating DNA base excision repair,apoptosis,and necrosis. It includes a DNA-binding domain with 23 zinc finger motifs,and a poly(ADP-ribose) polymerase catalytic domain | |
Licence : | Droits gérés |
Crédit: | Science Photo Library / Pasieka, Alfred |
Taille de l’image : | 5000 px × 3750 px |
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